Forbes by William A Haseltine 4/4/2022
This story is part of a larger mosaic of stories on the neurological consequences of Covid-19 and Post-Acute Sequelae of Covid-19 (PASC), also known as Long Covid.
Here, we discuss a series of studies examining the objective measures of blood and cerebrospinal fluid (CSF) that may offer clues as to how Covid-19 injures the brain. Estimates show that half of those hospitalized for neurological complications with Covid-19 continue to experience cognitive impairments. Even more concerning are the increasing reports of long-lasting cognitive symptoms among individuals that experienced mild or asymptomatic infections. It is clear that SARS-CoV-2 can significantly damage brain cells without direct infection. Systematic efforts to detect brain injury have failed to provide explicit evidence of inflammatory damage to brain cells.