UK Demential Research Institute 10/30/2020
A team of researchers from the UK Dementia Rearch Institute (DRI) have, for the first time, been able to accurately predict the extent of chronic neurodegeneration in people who have experienced traumatic brain injury, using an advanced type of MRI scanning. The results could help identify suitable candidates for clinical treatment trials, with the aim of preventing dementia post-injury.
Around 50 million people each year worldwide experience traumatic brain injury as a result of head injury. It is now widely recognised as a risk factor for dementia: in July, the Lancet added traumatic brain injury in mid-life to its list of modifiable risk factors for dementia, as part of an update to its Commission on dementia prevention, intervention and care.
However, the link between traumatic damage to the brain’s connecting nerve fibres (axons) and chronic neurodegeneration has never been well established in patients, and direct proof of it has until now been lacking.